Research questionCan machine learning models accurately predict the risk of early miscarriage following single vitrified-warmed blastocyst transfer (SVBT)?DesignA dual-center retrospective analysis of 1,664 SVBT cycles, including 308 early miscarriage cases, was conducted across two reproductive centers.Multiple machine learning models, such as Log
The extracellular matrix (ECM) provides Collections cues to direct mammogenesis, tumourigenesis and metastatic processes.Over the past several decades, two-dimensional (2D) culture models have been invaluable in furthering our understanding of the tumor microenvironment (TME), however, they still do not accurately emulate the associated biological
ABSTRACT Emerging coronaviruses (CoVs) Interface Board can cause severe diseases in humans and animals, and, as of yet, none of the currently available broad-spectrum drugs or vaccines can effectively control these diseases.Host antiviral proteins play an important role in inhibiting viral proliferation.One of the isoforms of cytoplasmic poly(A)-bi
Zoonotic infections are an imminent threat to human health.Pangolins were recently identified as carriers and intermediate hosts of coronaviruses.Previous research has shown that infection with coronaviruses activates an innate immune response upon sensing of viral RNA by interferon-induced with helicase C domain 1 (IFIH1), also known as MDA5.Here,